abstract：:The pathogenesis of hypertrophic scar (HS) is still poorly understood. Macrophages, especially the polarisation of that to M1 or M2, play a pivotal role in control of the degree of scar formation. Profiling of macrophage phenotypes in human specimens during long-term period of wound healing and HS formation may provid...

journal_title：International wound journal

authors： Chen L,Wang J,Li S,Yu Z,Liu B,Song B,Su Y

更新日期：2019-04-01 00:00:00

abstract：:It has been shown that pressure ulcer formation in critically ill paediatric patients increases morbidity and mortality. We sought to identify factors associated with pressure ulcer formation in paediatric patients on extracorporeal membrane oxygenation (ECMO). From December 2014 to 2015, we identified patients at our...

journal_title：International wound journal

authors： Tam SF,Mobargha A,Tobias J,Schad CA,Okochi S,Middlesworth W,Duron V

更新日期：2019-04-01 00:00:00

abstract：:Tendinopathy is a very common disease in the general population as well as in athletes. The aim of the present study was to examine the tendon thickness and cross-sectional area (CSA) in subjects with chronic mid-portion Achilles tendinopathy (AT) who engaged in either an eccentric exercise (EE) programme with vibrati...

journal_title：International wound journal

authors： Romero-Morales C,Javier Martín-Llantino P,Calvo-Lobo C,Palomo-López P,López-López D,Fernández-Carnero J,Rodríguez-Sanz D

更新日期：2019-04-01 00:00:00

abstract：:The aims of this randomised controlled study were to determine whether the application of silicone adhesive dressings with standard preventive care would reduce the impairment of skin integrity and to evaluate the subepidermal moisture (SEM) value in anatomical locations to predict impairment of skin integrity. Of the...

journal_title：International wound journal

authors： Lee YJ,Kim JY,Shin WY

更新日期：2019-03-01 00:00:00

abstract：:Chronic non-healing wounds are a burden in the Long-Term Care (LTC) sector, increasing costs, morbidity, and mortality and causing pain and suffering. The objective of this LTC Innovation pilot was to test the value of a promising new neuromuscular stimulation device in elevating the experience and satisfaction of the...

journal_title：International wound journal

authors： Harris C,Ramage D,Boloorchi A,Vaughan L,Kuilder G,Rakas S

更新日期：2019-02-01 00:00:00

abstract：:Negative pressure wound therapy (NPWT) is an established method for the faster wound healing of chronic non-healing wounds. It is also used for laparostomy wounds and healing of split skin grafts. The commercially available machine and the consumables for NPWT are very expensive and economically not feasible in develo...

journal_title：International wound journal

authors： Gopal SV,Solomon A

更新日期：2019-02-01 00:00:00

abstract：:Chronic wounds are a significant problem in Australia. The health care-related costs of chronic wounds in Australia are considerable, equivalent to more than AUD $3.5 billion, approximately 2% of national health care expenditure. Chronic wounds can also have a significant negative impact on the health-related quality ...

journal_title：International wound journal

authors： McCosker L,Tulleners R,Cheng Q,Rohmer S,Pacella T,Graves N,Pacella R

更新日期：2019-02-01 00:00:00

abstract：:Venous or mixed ulcers are common and invalidating. Cutaneous transplants may be necessary if conventional treatment is ineffective. We evaluated the performance of Cellutome in promoting the healing of venous or mixed ulcers 2 months after grafting. This was a retrospective, multi-centric, descriptive study of patien...

journal_title：International wound journal

authors： Vinceneux Talvande B,Carvalho Lallement P,Safa G,Journet Tollhupp J,Lembelembe JP,Blaise S,Maillard H

更新日期：2018-12-01 00:00:00

abstract：:Venous leg ulcers are the most common form of non-healing leg ulcers. They are subjected to treatments such as topical medications, dressings, and compression therapies. This can lead to exposure to a number of allergens with subsequent sensitisation and contact dermatitis of the regional skin. This may contribute to ...

journal_title：International wound journal

authors： Rai R,Shenoy MM,Viswanath V,Sarma N,Majid I,Dogra S

更新日期：2018-08-01 00:00:00

abstract：:We present a new surgical modification to allow propeller perforator flaps to cover pressure sores at various locations. We used a propeller perforator flap concept based on the detection of newly formed perforator vessels located 1 cm from the wound margin and stimulated by the chronic inflammation process. Between J...

journal_title：International wound journal

authors： Kelahmetoglu O,Van Landuyt K,Yagmur C,Sommeling CE,Keles MK,Tayfur V,Simsek T,Demirtas Y,Guneren E

更新日期：2017-12-01 00:00:00

abstract：:Enzymatic debridement with collagenase is a technique that is commonly used in clinical practice. This systematic review examines the effect of collagenase on all kinds of wounds, compared to an alternative therapy, on wound healing, wound bed characteristics, cost-effectiveness and the occurrence of adverse events. W...

journal_title：International wound journal

authors： Patry J,Blanchette V

更新日期：2017-12-01 00:00:00

abstract：:Vacuum-assisted closure (VAC) therapy is a sophisticated system that maintains a closed, humid, sterile and isolated environment. Wound infection is considered a relative contraindication. The objective of this study is to extend the indications for VAC therapy to include infected wounds by demonstrating its ability t...

journal_title：International wound journal

authors： Lo Torto F,Ruggiero M,Parisi P,Borab Z,Sergi M,Carlesimo B

更新日期：2017-12-01 00:00:00

abstract：:Management of small-bowel fistulas which are in an open abdomen and have no soft tissue overlay or a fistula tract involves many complications and challenges. Controlling the local leakage of enteric contents has a central role in the success of medical treatment. There are several methods to deal with fistula dischar...

journal_title：International wound journal

authors： Miranda LE,Miranda AC

更新日期：2017-12-01 00:00:00

abstract：:The aim of the study was to assess the reliability of measuring the cross-sectional area of diabetic foot ulcers using Image J software. The inter- and intra-rater reliability of ulcer area measures were assessed using digital images of acetate tracings of ulcers of the foot affecting 31 participants in an off-loading...

journal_title：International wound journal

authors： Jeffcoate WJ,Musgrove AJ,Lincoln NB

更新日期：2017-12-01 00:00:00

abstract：:There are many porcine burn models that create burns using different materials (e.g. metal, water) and different burn conditions (e.g. temperature and duration of exposure). This review aims to determine whether a pooled analysis of these studies can provide insight into the burn materials and conditions required to c...

journal_title：International wound journal

authors： Andrews CJ,Cuttle L

更新日期：2017-12-01 00:00:00

abstract：:Increasing evidence within the literature has identified the presence of biofilms in chronic wounds and proposed that they contribute to delayed wound healing. This research aimed to investigate the presence of biofilm in diabetic foot ulcers (DFUs) using microscopy and molecular approaches and define if these are pre...

journal_title：International wound journal

authors： Johani K,Malone M,Jensen S,Gosbell I,Dickson H,Hu H,Vickery K

更新日期：2017-12-01 00:00:00

abstract：:In addition to clinical signs of infection (e.g. inflammation, purulence and pain), a microbial count of ≥105 colony-forming units/g has historically been used to define wound infection. However, it is increasingly recognised that, rather than a high bioburden level alone being detrimental to wound healing, it is the ...

journal_title：International wound journal

authors： Lindsay S,Oates A,Bourdillon K

更新日期：2017-12-01 00:00:00

abstract：:Keloids are fibroproliferative skin disorders characterised clinically by continuous horizontal progression and post-surgical recurrence and histologically by the accumulation of collagen and fibroblast ingredients. Till now, their aetiology remains clear, which may cover genetic, environmental and metabolic factors. ...

journal_title：International wound journal

authors： Huang C,Liu L,You Z,Wang B,Du Y,Ogawa R

更新日期：2017-10-01 00:00:00

abstract：:A 6-month-old Caucasian baby is described with a postaxial polydactyly of the letf foot. Radiographic examination revealed the accessory digit was composed of soft tissue, some with a tiny osseous element, originated from around the metatarsophalangeal joint, defined by floating type (FT). The parents had consistent d...

journal_title：International wound journal

authors： López-López D,Becerro-de-Bengoa-Vallejo R,Losa-Iglesias ME,Bautista Casasnovas AL

更新日期：2017-10-01 00:00:00

abstract：:The purpose of this analysis was to evaluate the use of DermaPure, a decellularised human skin allograft, in the treatment of a variety of challenging wounds. This retrospective observational analysis reviewed a total of 37 patients from 29 different wound clinics across the USA. Each patient received one application ...

journal_title：International wound journal

authors： Kimmel H,Gittleman H

更新日期：2017-08-01 00:00:00

abstract：:Foreign modelling agent reactions (FMAR) are the result of the injection of unapproved high-viscosity fluids with the purpose of cosmetic body modelling. Its consequences lead to ulceration, disfigurement and even death, and it has reached epidemic proportions in several regions of the world. We describe a series of p...

journal_title：International wound journal

authors： Martínez-Villarreal AA,Asz-Sigall D,Gutiérrez-Mendoza D,Serena TE,Lozano-Platonoff A,Sanchez-Cruz LY,Toussaint-Caire S,Domínguez-Cherit J,López-García LA,Cárdenas-Sánchez A,Contreras-Ruiz J

更新日期：2017-06-01 00:00:00

abstract：:Iodine-based products are antibacterial. The small iodine molecular size is ideally suited to treat surface critical colonisation. Inadine is a 10% povidone iodine dressing with the equivalent of 1% available iodine that is easily extracted from the viscose backing by serum or exudate. The use of hydrophilic polyethyl...

journal_title：International wound journal

authors： Sibbald RG,Elliott JA

更新日期：2017-04-01 00:00:00

abstract：:Acellular dermal matrices can successfully heal wounds. This study's goal was to compare clinical outcomes of a novel, open-structure human reticular acellular dermis matrix (HR-ADM) to facilitate wound closure in non-healing diabetic foot ulcers (DFUs) versus DFUs treated with standard of care (SOC). Following a 2-we...

journal_title：International wound journal

authors： Zelen CM,Orgill DP,Serena T,Galiano R,Carter MJ,DiDomenico LA,Keller J,Kaufman J,Li WW

更新日期：2017-04-01 00:00:00

abstract：:This is a prospective study with the aim to determine specific patterns of burn wound bacterial colonisation and antimicrobial resistance profiles. There is a high incidence of infections and septicaemia in post-burn patients, which, in turn, are associated with high morbidity and mortality, a fact that compelled us t...

journal_title：International wound journal

authors： Mir MA,Khurram MF,Khan AH

更新日期：2017-02-01 00:00:00

abstract：:The critical problem of post-burn depigmentation is the lacking normal melanocytes. Auto-skin grafting and autologous non-cultured epidermal cell suspension have been used to improve the appearance. However, a large amount of skin graft is required of donor sites in the former method, while the latter method is though...

journal_title：International wound journal

authors： Chen B,Xu M,Li B

更新日期：2017-02-01 00:00:00

abstract：:Current embodiments of negative pressure wound therapy (NPWT) create a hermetically sealed chamber at the surface of the body using polyurethane foam connected to a vacuum pump, which is then covered by a flexible adhesive drape. Commercially available NPWT systems routinely use flexible polyethylene films that have a...

journal_title：International wound journal

authors： Daar DA,Wirth GA,Evans GR,Carmean M,Gordon IL

更新日期：2017-02-01 00:00:00

abstract：:Facial traumatic events are commonly encountered in plastic and reconstructive surgery. Primary reconstruction is a reliable procedure with function and aesthetic considerations. We conduct a retrospective study of the experience of reconstructing facial traumatic defects in the first stage. One hundred and thirty-two...

journal_title：International wound journal

authors： Chen B,Song H,Gao Q,Xu M,Chai J

更新日期：2017-02-01 00:00:00

abstract：:Skin grafting is one of the most common surgical procedures in the area of non-healing wounds by which skin or a skin substitute is placed over a wound to replace and regenerate the damaged skin. Chronic leg ulcers are an important problem and a major source of expense for Western countries and for which many differen...

journal_title：International wound journal

authors： Serra R,Rizzuto A,Rossi A,Perri P,Barbetta A,Abdalla K,Caroleo S,Longo C,Amantea B,Sammarco G,de Franciscis S

更新日期：2017-02-01 00:00:00

abstract：:Senescent fibroblasts, which are present in chronic ulcers, are the reason for the wound becoming chronic. In this study, we introduce full-thickness micro skin grafts in the ulcer, a surgical technique known as a 'nested graft', which gave encouraging results leading to complete wound healing in all patients. The ass...

journal_title：International wound journal

authors： Gualdi G,Crotti S,Monari P,Calzavara-Pinton P,Vitali M,Baronio M,Lougaris V

更新日期：2016-12-01 00:00:00

abstract：:Ischaemia reperfusion (I/R) injury refers to tissue damage caused when blood supply returns to the tissue after a period of ischaemia. Matrix metalloproteinases (MMPs), neutrophil gelatinase-associated lipocalin (NGAL) and cytokines are biomarkers involved in several vascular complications. The aim of this study was t...

journal_title：International wound journal

authors： de Franciscis S,De Caridi G,Massara M,Spinelli F,Gallelli L,Buffone G,Caliò FG,Butrico L,Grande R,Serra R

更新日期：2016-10-01 00:00:00

abstract：:Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialised dermatological wound care centers were analysed. The patient cohort comprised 567 females and 433 males with an average age ...

journal_title：International wound journal

authors： Jockenhöfer F,Gollnick H,Herberger K,Isbary G,Renner R,Stücker M,Valesky E,Wollina U,Weichenthal M,Karrer S,Kuepper B,Roesch A,Dissemond J

更新日期：2016-10-01 00:00:00

abstract：:Podologists are nurses who care for the diabetic foot (orthotics, offloading devices, blisters, calluses, treatment of fungus infection and patient education). In contrast to podiatrists, they are not qualified to perform any surgical treatment or wound care. We analysed whether there is an association between the dec...

journal_title：International wound journal

authors： Kröger K,Moysidis T,Feghaly M,Schäfer E,Bufe A,Initiative Chronische Wunden e.V., Germany.

更新日期：2016-10-01 00:00:00

abstract：:Globally, wound care costs the health care system 2-3% of the total expenditure on health, which equates to several billion dollars annually. To date, there are little data on the cost and healing rates of various wounds. This has been partly because of the difficulty in tracking wound management as the majority of wo...

journal_title：International wound journal

authors： Khalil H,Cullen M,Chambers H,Carroll M,Walker J

更新日期：2016-10-01 00:00:00

abstract：:Biological alternatives to synthetic meshes are increasingly utilised in complex abdominal wall reconstruction. There is a lack of evidence demonstrating that non-cross-linked porcine acellular dermal matrix vascularizes and integrates with human tissue in suboptimal wound conditions. We aimed to evaluate these proper...

journal_title：International wound journal

authors： Gowda AU,Chang SM,Chopra K,Matthews JA,Sabino J,Stromberg JA,Zahiri HR,Pinczewski J,Holton LH 3rd,Silverman RP,Singh DP

更新日期：2016-10-01 00:00:00

abstract：:Negative pressure wound therapy with instillation and dwell time (NPWTi-d) is an adjunctive therapy that can be used in the management of complex wounds with infection. NPWTi-d incorporates the intermittent instillation of a topical solution to the wound in a programmed manner. Unlike standard negative pressure wound ...

journal_title：International wound journal

authors： Anghel EL,Kim PJ,Attinger CE

更新日期：2016-09-01 00:00:00

abstract：:Wound bed preparation (WBP) is an integral part of the care programme for chronic wounds. The acronym TIME is used in the context of WBP and describes four barriers to healing in chronic wounds; namely, dead Tissue, Infection and inflammation, Moisture imbalance and a non-migrating Edge. Larval debridement therapy (LD...

journal_title：International wound journal

authors： Pritchard DI,Čeřovský V,Nigam Y,Pickles SF,Cazander G,Nibbering PH,Bültemann A,Jung W

更新日期：2016-08-01 00:00:00

abstract：:The aim of this systematic review was to determine the supporting evidence for the clinical use of hydrogel dressings as a first aid measure for burn wound management in the pre-hospital setting. Two authors searched three databases (Ovid Medline, Ovid Embase and The Cochrane Library) for relevant English language art...

journal_title：International wound journal

authors： Goodwin NS,Spinks A,Wasiak J

更新日期：2016-08-01 00:00:00

abstract：:Covering the reconstructed area with a healthy soft-tissue envelope is a major challenge after limb-sparing surgery in patients with malignant bone and soft-tissue tumours. Negative pressure wound therapy (NPWT) of open wounds hastens healing and minimises the requirement for complex reconstructive soft-tissue surgery...

journal_title：International wound journal

authors： Mermerkaya U,Bekmez S,Alkan E,Ayvaz M,Tokgozoglu M

更新日期：2016-06-01 00:00:00

abstract：:Keratin proteins have been shown to play a key role in wound healing. Controlled keratin gene (KRT) expression promotes cell growth, migration and differentiation, and as an example of the importance of keratin proteins, absence of KRT17 has been shown to delay wound closure. In addition, downregulation of KRT6 and KR...

journal_title：International wound journal

authors： Batzer AT,Marsh C,Kirsner RS

更新日期：2016-02-01 00:00:00

abstract：:Although chronic wounds have a high socio-economic impact, data on comparative effectiveness of treatments are rare. UrgoStart(®) is a hydroactive dressing containing a nano-oligosaccharide factor (NOSF). This study aimed at evaluating the cost-effectiveness of this NOSF-containing wound dressing in vascular leg ulcer...

journal_title：International wound journal

authors： Augustin M,Herberger K,Kroeger K,Muenter KC,Goepel L,Rychlik R

更新日期：2016-02-01 00:00:00